Grain consumption and risk of gastric cancer: a meta-analysis.

Department of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, China. Department of Gastroenterology, Affiliated Hospital of Youjiang Medical University for Nationlities, Baise, China. Department of Gastroenterology, Xiangyang Central Hospital, XiangYang, China. Department of Endocrinology, Affiliated Hospital of Xiangnan University, Chenzhou, China.

International journal of food sciences and nutrition. 2020;(2):164-175
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Abstract

This study evaluated the relationship between grain consumption and the risk of gastric cancer. A total of 19 studies met the inclusion criteria. For whole grain consumption, there was a 13% reduction in the risk of gastric cancer (p = .003), and a subgroup analysis showed that a large amount of whole grain consumption reduced the risk of gastric cancer by 44% (p < .001). For refined grain consumption, there was a 36% increase in the risk of gastric cancer (p < .001); a subgroup analysis showed that a large and a moderate amount of refined grain consumption increased the risk of gastric cancer by 63% (p < .001) and 28% (p < .001), respectively. A large intake of whole grains might be protective against gastric cancer, whereas the ingestion of refined cereals may be a risk factor for gastric cancer. Moreover, the risk of cancer increases with the increase of refined grain intake.

Methodological quality

Publication Type : Meta-Analysis

Metadata

MeSH terms : Stomach Neoplasms